In their sophomore year at Greendale, the study group decides to take Anthropology 101 together. The course is taught by Professor June Bauer in the Anthropology classroom. The class would later be taught by Professor Ian Duncan after Bauer was suspended for attacking a student. Its first appearance was in the Season Two episode "Anthropology 101"; its last appearance was in the episode "A Fistful of Paintballs".
- "Anthropology 101": Professor June Bauer welcomes her the students to her class and shoots Star-Burns with a paralyzing dart when he interrupts her opening monologue. She asks the students to form a tribe for their first assignment. For their next assignment she asks that they analyze a box of random tools and try to figure out which is the most important to their survival. After she is finished explaining Jeff challenges Britta to a "love" competition annoyed at how she has spun what happened between them at the "Tranny Dance" last year for her own benefit. When this contest leads to unexpected fallout and causes a rift between the study group, Jeff tries to make up for it the following day in Anthropology class. He issues an apology to the group through his presentation of his class assignment. Bauer rejects his explanation and attacks him with a combination of the tools she gave them for the project. She is then suspended from school for an indefinite amount of time.
- "The Psychology of Letting Go": Despite having no educational background on the subject, Professor Ian Duncan is brought in to replace Bauer as the Anthropology teacher. He and Ben Chang get into a brief argument due to the restraining order Ian has against him after their fight at the "Tranny Dance". Later, Pierce brings his recently deceased mother's Energon pod to the classroom. Duncan soon discovers the advantages to his restraining order and starts abusing it forcing Chang to leave the classroom. With Chang gone, a discussion begins of Pierce's religious beliefs and Duncan is intrigued when he mentions the church has a mixer coming up with lots of alcoholic beverages available. The conversation is interrupted when an attractive female students enters the classroom looking for "Anesthesiology" which Duncan immeditraley replies it is.
- "Messianic Myths and Ancient Peoples": Duncan decides that the curriculum of the class should be them watching various Youtube videos to fully understand the nature of man.
- "Asian Population Studies": After Winter break is over, the second semester of Anthropology begins and a now sober Duncan promises to be more serious in his teaching of the class. Rich takes Annie's advice and decides to sign up for the course much to Jeff's chagrin.
- "Applied Anthropology and Culinary Arts": When the time for the Anthropology finals has come, Duncan shows himself to have fallen off the wagon and invites the class to bring their own alcoholic drinks to class. His plans to unwind and coast through the last class are undone when Dean Pelton unexpectedly drops by with a reporter form Dean monthly magazine to observe the class in action. Duncan excuses himself from the class and never returns leaving evryone else to deal with a crisis that soon develops. Shirley goes into labor and because of riot taking place in the school parking lot they are unable to drive her to a hospital. Britta is forced to delver the baby in the classroom with Abed's assistance.
- "A Fistful of Paintballs": The classroom is shown to have gotten wrecked during the 2011 Paintball game. Annie chases after Ben Chang and ends up in the Anthropology classroom only to be ambushed by The Black Rider. She is saved by the timely arrival of Jeff and Abed and a brief paintball gu battle ensues between the three of them inside the classroom before the Black Rider retreats.
- "For A Few Paintballs More": The remaining Greendale paintball players gather inside the Anthropology classroom to discuss a new threat which has inserted itself into the game, a City College paintball army. A radio controlled toy car with a paintball grenade payload enters the classroom interrupting their conversation. Before it could explode, Magnitude sacrifices himself by jumping on top of it. The remaining students unite in honor of their fallen comrade and resolve to take back the school form the City College invaders.