Nurse Jackie is the resident campus nurse at the Greendale Student Health Center. A somewhat bumbling health care provider, he often comes off as slightly creepy to all of his female patients. His first appearance was in the Season One episode "Home Economics". He is portrayed by actor/comedian Patton Oswalt.
Nurse Jackie is first seen in the study group's first year at Greendale when he treated Annie after she pretended to be sick. She is accompanied by Troy whom Jackie mistakenly assumes is her boyfriend. After examining her he finds that she's in good health and is about to release her when she fakes feeling unwell to prevent Troy from going on his date with Randi. Jackie tells her she has to stay in his care for observation and be quarantined. He then gives Troy a pack of condoms sending him on his way so he can go on his date. After he leaves, Jackie turns his attention back to Annie and makes an awkward pass at her ("Home Economics"). He returns in the group's second year to give Jeff the results of his medical test. Jackie is amused when Jeff takes the news that his cholesterol is too high very badly. Jackie then tries to get Jeff to accept the truth that everyone's health eventually deteriorates even if they work hard to remain in good shape. Jeff leaves the clinic devastated and is later heard screaming, "There is no God!" outside. Jackie laughs at his reaction before turning to his next patient and making a creepy remark about the pap test he's about to administer to her ("The Psychology of Letting Go").
- “I'm kinda the Hawkeye around here so it's kind of a... Are you seeing anybody?”— Nurse Jackie
- “I treat my body like a temple!”— Jeff upon learning he has high cholesterol
- “I can't be the first person to tell you that the temple doesn't last forever. I mean it's made of hamburger. This is a temple of doom and you know what: like the real Temple of Doom, it represents the inconvenient fact that all good things--be they people or movie franchises--eventually collapse into sagging, sloppy, rotten piles of hard-to-follow nonsense.”— Nurse Jackie